HCSGD entry for CERS5
1. General information
| Official gene symbol | CERS5 |
|---|---|
| Entrez ID | 91012 |
| Gene full name | ceramide synthase 5 |
| Other gene symbols | LASS5 Trh4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IDA IEA | biological_process |
| GO:0050291 | Sphingosine N-acyltransferase activity | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4944599635 | 0.6572750617 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0999851433 |
| GSE13712_SHEAR | Down | -0.1239065568 |
| GSE13712_STATIC | Up | 0.0452611202 |
| GSE19018 | Up | 0.2386155290 |
| GSE19899_A1 | Down | -0.0147308190 |
| GSE19899_A2 | Down | -0.0328517208 |
| PubMed_21979375_A1 | Down | -0.0700134893 |
| PubMed_21979375_A2 | Down | -0.0339739126 |
| GSE35957 | Up | 0.2935730345 |
| GSE36640 | Up | 0.4975188370 |
| GSE54402 | Down | -0.1900043040 |
| GSE9593 | Up | 0.2546386764 |
| GSE43922 | Down | -0.0410903027 |
| GSE24585 | Up | 0.5138250377 |
| GSE37065 | Down | -0.0593356825 |
| GSE28863_A1 | Up | 0.0189396909 |
| GSE28863_A2 | Down | -0.0148985082 |
| GSE28863_A3 | Down | -0.5078096029 |
| GSE28863_A4 | Up | 0.0445510347 |
| GSE48662 | Up | 0.1305362102 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042119 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
