HCSGD entry for ISX


1. General information

Official gene symbolISX
Entrez ID91464
Gene full nameintestine-specific homeobox
Other gene symbolsPix-1 RAXLX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:1901738Regulation of vitamin A metabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55664798070.93227896360.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0033386381
GSE13712_SHEARUp0.0279730535
GSE13712_STATICUp0.0727149255
GSE19018Up0.0395857054
GSE19899_A1Up0.1066017154
GSE19899_A2Up0.0898463196
PubMed_21979375_A1Down-0.0389835795
PubMed_21979375_A2Down-0.0424085361
GSE35957Up0.0968506641
GSE36640Up0.2384095988
GSE54402Down-0.1172264444
GSE9593Down-0.0304967961
GSE43922Up0.0797166882
GSE24585Up0.0236930892
GSE37065Up0.0089004851
GSE28863_A1Up0.0009778099
GSE28863_A2Up0.0225839582
GSE28863_A3Up0.1943977406
GSE28863_A4Up0.1732941465
GSE48662Down-0.0110123720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-3928-3pMIMAT0018205MIRT052890CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.