HCSGD entry for DYRK1B
1. General information
| Official gene symbol | DYRK1B |
|---|---|
| Entrez ID | 9149 |
| Gene full name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| Other gene symbols | MIRK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0004672 | Protein kinase activity | IDA IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004712 | Protein serine/threonine/tyrosine kinase activity | IEA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0007520 | Myoblast fusion | IEA | biological_process |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1905746514 | 0.8594555146 | 0.8480330347 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0254863218 |
| GSE13712_SHEAR | Down | -0.4659807869 |
| GSE13712_STATIC | Down | -0.0410920483 |
| GSE19018 | Up | 0.1831765132 |
| GSE19899_A1 | Up | 0.0165322683 |
| GSE19899_A2 | Up | 0.2211512633 |
| PubMed_21979375_A1 | Up | 0.0103286445 |
| PubMed_21979375_A2 | Up | 0.0761294669 |
| GSE35957 | Up | 0.0112723086 |
| GSE36640 | Up | 0.1199737128 |
| GSE54402 | Up | 0.0645808777 |
| GSE9593 | Down | -0.0240927790 |
| GSE43922 | Up | 0.0530165988 |
| GSE24585 | Up | 0.3449342269 |
| GSE37065 | Down | -0.2196750154 |
| GSE28863_A1 | Up | 0.0970887712 |
| GSE28863_A2 | Up | 0.0399488738 |
| GSE28863_A3 | Up | 0.4365371408 |
| GSE28863_A4 | Up | 0.0100168385 |
| GSE48662 | Up | 0.3049687987 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016969 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-320c | MIMAT0005793 | MIRT036171 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037892 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-1-3p | MIMAT0004674 | MIRT038537 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043128 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044780 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045408 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
