HCSGD entry for LPAR2
1. General information
| Official gene symbol | LPAR2 |
|---|---|
| Entrez ID | 9170 |
| Gene full name | lysophosphatidic acid receptor 2 |
| Other gene symbols | EDG-4 EDG4 LPA-2 LPA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000187 | Activation of MAPK activity | IEA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA TAS | biological_process |
| GO:0007202 | Activation of phospholipase C activity | TAS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | TAS | biological_process |
| GO:0008289 | Lipid binding | TAS | molecular_function |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030139 | Endocytic vesicle | IDA | cellular_component |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0035025 | Positive regulation of Rho protein signal transduction | IEA | biological_process |
| GO:0070915 | Lysophosphatidic acid receptor activity | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3977558185 | 0.8904148551 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0627070548 |
| GSE13712_SHEAR | Up | 0.1576807275 |
| GSE13712_STATIC | Up | 0.0806363052 |
| GSE19018 | Up | 0.0985261677 |
| GSE19899_A1 | Down | -0.0619678650 |
| GSE19899_A2 | Up | 0.3038951214 |
| PubMed_21979375_A1 | Down | -0.0232013712 |
| PubMed_21979375_A2 | Up | 0.1782798202 |
| GSE35957 | Up | 0.0499292775 |
| GSE36640 | Up | 0.4864092428 |
| GSE54402 | Down | -0.0289128269 |
| GSE9593 | Up | 0.1563509697 |
| GSE43922 | Up | 0.0491474408 |
| GSE24585 | Up | 0.0313789601 |
| GSE37065 | Down | -0.1898223535 |
| GSE28863_A1 | Down | -0.2401948819 |
| GSE28863_A2 | Down | -0.0436864417 |
| GSE28863_A3 | Up | 0.1427607645 |
| GSE28863_A4 | Up | 0.1317985593 |
| GSE48662 | Down | -0.0183981900 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 12646237 | EDG-1 and EDG-4 were unchanged, but EDG-2 and EDG-7 were reduced with age |
Entries Per Page
Displaying Page of
