HCSGD entry for CABLES1
1. General information
| Official gene symbol | CABLES1 |
|---|---|
| Entrez ID | 91768 |
| Gene full name | Cdk5 and Abl enzyme substrate 1 |
| Other gene symbols | CABL1 CABLES HsT2563 IK3-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0016538 | Cyclin-dependent protein serine/threonine kinase regulator activity | IEA | molecular_function |
| GO:0051301 | Cell division | IEA | biological_process |
| GO:0051302 | Regulation of cell division | IEA | biological_process |
| GO:0051726 | Regulation of cell cycle | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4360076137 | 0.0547532541 | 0.9999902473 | 0.4412869871 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1423052106 |
| GSE13712_SHEAR | Down | -0.0232560921 |
| GSE13712_STATIC | Down | -0.0111072840 |
| GSE19018 | Down | -0.2405845459 |
| GSE19899_A1 | Down | -0.4482004024 |
| GSE19899_A2 | Up | 0.0419897190 |
| PubMed_21979375_A1 | Up | 0.4463018171 |
| PubMed_21979375_A2 | Up | 0.6926460438 |
| GSE35957 | Up | 0.7973424700 |
| GSE36640 | Up | 0.6818992416 |
| GSE54402 | Down | -1.1827780858 |
| GSE9593 | Down | -0.2334580691 |
| GSE43922 | Down | -0.2180586467 |
| GSE24585 | Down | -0.9639398222 |
| GSE37065 | Down | -0.0144704748 |
| GSE28863_A1 | Up | 0.0577054938 |
| GSE28863_A2 | Up | 0.0540801538 |
| GSE28863_A3 | Up | 0.2957834652 |
| GSE28863_A4 | Down | -0.0083919134 |
| GSE48662 | Down | -0.5217401349 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022619 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040768 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041951 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051451 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
