HCSGD entry for CD247

1. General information

Official gene symbolCD247
Entrez ID919
Gene full nameCD247 molecule
Other gene symbolsCD3-ZETA CD3H CD3Q CD3Z T3Z TCRZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processTASbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0042101T cell receptor complexIDAcellular_component
GO:0042105Alpha-beta T cell receptor complexIEAcellular_component
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityNASmolecular_function
GO:0045087Innate immune responseTASbiological_process
GO:0050690Regulation of defense response to virus by virusTASbiological_process
GO:0050776Regulation of immune responseTASbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70577272900.85480643970.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1458814962
GSE13712_SHEARUp0.1255115676
GSE13712_STATICDown-0.0097170936
GSE19018Down-0.0065880149
GSE19899_A1Up0.1212066770
GSE19899_A2Up0.1249609996
PubMed_21979375_A1Down-0.2366296605
PubMed_21979375_A2Up0.0020997994
GSE35957Up0.0441084883
GSE36640Down-0.1149044423
GSE54402Up0.0533900629
GSE9593Down-0.0026278114
GSE43922Up0.0004780093
GSE24585Up0.0701339911
GSE37065Up0.0197084798
GSE28863_A1Down-0.0038649690
GSE28863_A2Up0.0379199944
GSE28863_A3Up0.1531109800
GSE28863_A4Up0.1095395450
GSE48662Up0.1231604900

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MuromonabDB00075 BTD00005 | BIOD00005

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-346MIMAT0000773MIRT004233MicroarrayFunctional MTI (Weak)16822819
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.