HCSGD entry for LGI1
1. General information
| Official gene symbol | LGI1 |
|---|---|
| Entrez ID | 9211 |
| Gene full name | leucine-rich, glioma inactivated 1 |
| Other gene symbols | ADLTE ADPAEF ADPEAF EPITEMPIN EPT ETL1 IB1099 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007411 | Axon guidance | IMP | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030307 | Positive regulation of cell growth | IMP | biological_process |
| GO:0031175 | Neuron projection development | IMP | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0050806 | Positive regulation of synaptic transmission | ISS | biological_process |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5669249725 | 0.7371423578 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0533593703 |
| GSE13712_SHEAR | Down | -0.2332766670 |
| GSE13712_STATIC | Down | -0.0565843037 |
| GSE19018 | Up | 0.1506361996 |
| GSE19899_A1 | Up | 0.1186461996 |
| GSE19899_A2 | Down | -0.0268867198 |
| PubMed_21979375_A1 | Down | -0.2022757451 |
| PubMed_21979375_A2 | Up | 0.0525319974 |
| GSE35957 | Up | 0.1918846066 |
| GSE36640 | Up | 0.2057518607 |
| GSE54402 | Up | 0.0878216291 |
| GSE9593 | Down | -0.1318410905 |
| GSE43922 | Up | 0.0216926083 |
| GSE24585 | Up | 0.5494462877 |
| GSE37065 | Down | -0.0588944460 |
| GSE28863_A1 | Down | -0.0724148016 |
| GSE28863_A2 | Up | 0.0069527058 |
| GSE28863_A3 | Up | 0.1383453496 |
| GSE28863_A4 | Down | -0.0420353232 |
| GSE48662 | Down | -0.0328378353 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
