HCSGD entry for MRRF
1. General information
| Official gene symbol | MRRF |
|---|---|
| Entrez ID | 92399 |
| Gene full name | mitochondrial ribosome recycling factor |
| Other gene symbols | MRFF MTRRF RRF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006412 | Translation | IEA | biological_process |
| GO:0032790 | Ribosome disassembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7671280005 | 0.0192995213 | 0.9999902473 | 0.2708458955 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4179690383 |
| GSE13712_SHEAR | Down | -0.0716947640 |
| GSE13712_STATIC | Down | -0.0609025184 |
| GSE19018 | Down | -0.2842191342 |
| GSE19899_A1 | Down | -0.1340600784 |
| GSE19899_A2 | Down | -0.3907231437 |
| PubMed_21979375_A1 | Down | -0.0892531395 |
| PubMed_21979375_A2 | Down | -0.8117019545 |
| GSE35957 | Down | -0.5893206144 |
| GSE36640 | Down | -0.3051688355 |
| GSE54402 | Up | 0.0053831285 |
| GSE9593 | Down | -0.3577840203 |
| GSE43922 | Down | -0.1520453399 |
| GSE24585 | Down | -0.5313324028 |
| GSE37065 | Up | 0.0718514643 |
| GSE28863_A1 | Down | -0.3840044905 |
| GSE28863_A2 | Up | 0.1221584940 |
| GSE28863_A3 | Down | -0.0037350524 |
| GSE28863_A4 | Up | 0.0580045282 |
| GSE48662 | Down | -0.2781968155 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031902 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19563823 | The expression of some genes, including EGR 1/3 and MRRF, was controlled by LPA similarly in young and senescent cells, showing a typical time-dependent up-and-down expression profile |
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