HCSGD entry for DHRS3
1. General information
| Official gene symbol | DHRS3 |
|---|---|
| Entrez ID | 9249 |
| Gene full name | dehydrogenase/reductase (SDR family) member 3 |
| Other gene symbols | DD83.1 RDH17 Rsdr1 SDR1 SDR16C1 retSDR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | TAS | molecular_function |
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0042572 | Retinol metabolic process | TAS | biological_process |
| GO:0042622 | Photoreceptor outer segment membrane | TAS | cellular_component |
| GO:0052650 | NADP-retinol dehydrogenase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1395186961 | 0.0173612857 | 0.7512830606 | 0.2577362662 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0191348841 |
| GSE13712_SHEAR | Up | 0.2974528219 |
| GSE13712_STATIC | Up | 0.4773873788 |
| GSE19018 | Up | 0.6315843444 |
| GSE19899_A1 | Down | -1.2664739259 |
| GSE19899_A2 | Down | -0.0352825931 |
| PubMed_21979375_A1 | Down | -1.1577141888 |
| PubMed_21979375_A2 | Up | 0.8108469509 |
| GSE35957 | Down | -1.0387850944 |
| GSE36640 | Up | 0.9247281446 |
| GSE54402 | Down | -1.0304489785 |
| GSE9593 | Down | -1.9150559368 |
| GSE43922 | Up | 0.0491072950 |
| GSE24585 | Up | 0.1360337792 |
| GSE37065 | Down | -0.5965650391 |
| GSE28863_A1 | Up | 0.3903635352 |
| GSE28863_A2 | Down | -0.4952699246 |
| GSE28863_A3 | Up | 0.2474633536 |
| GSE28863_A4 | Down | -0.3693520965 |
| GSE48662 | Up | 0.4434088401 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin A | DB00162 | NUTR00007 | APRD00486 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017134 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022260 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049042 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
