HCSGD entry for CD8B

1. General information

Official gene symbolCD8B
Entrez ID926
Gene full nameCD8b molecule
Other gene symbolsCD8B1 LEU2 LY3 LYT3 P37
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006955Immune responseNASbiological_process
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayNASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0015026Coreceptor activityNASmolecular_function
GO:0016032Viral processTASbiological_process
GO:0031901Early endosome membraneTAScellular_component
GO:0042101T cell receptor complexNAScellular_component
GO:0042110T cell activationNASbiological_process
GO:0042288MHC class I protein bindingNASmolecular_function
GO:0050690Regulation of defense response to virus by virusTASbiological_process
GO:0050776Regulation of immune responseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64531474490.94928247410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0204173465
GSE13712_SHEARDown-0.0543511278
GSE13712_STATICDown-0.0107887539
GSE19018Up0.0712011289
GSE19899_A1Up0.0960863089
GSE19899_A2Up0.1909715727
PubMed_21979375_A1Up0.3143998399
PubMed_21979375_A2Down-0.0258909928
GSE35957Up0.0534127458
GSE36640Up0.0144546268
GSE54402Up0.0659861799
GSE9593Up0.0278051923
GSE43922Up0.0159608864
GSE24585Up0.0538237196
GSE37065Up0.0108309623
GSE28863_A1Up0.1171697997
GSE28863_A2Up0.0328937007
GSE28863_A3Up0.1901082538
GSE28863_A4Down-0.0048219167
GSE48662Down-0.0338825872

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.