HCSGD entry for HELB
1. General information
| Official gene symbol | HELB |
|---|---|
| Entrez ID | 92797 |
| Gene full name | helicase (DNA) B |
| Other gene symbols | hDHB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004003 | ATP-dependent DNA helicase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005658 | Alpha DNA polymerase:primase complex | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006260 | DNA replication | IMP | biological_process |
| GO:0006269 | DNA replication, synthesis of RNA primer | IDA IEA | biological_process |
| GO:0017116 | Single-stranded DNA-dependent ATP-dependent DNA helicase activity | IDA | molecular_function |
| GO:0032508 | DNA duplex unwinding | IDA | biological_process |
| GO:0043141 | ATP-dependent 5'-3' DNA helicase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1189395046 | 0.8035576308 | 0.7070870684 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0439212403 |
| GSE13712_SHEAR | Up | 0.0414218819 |
| GSE13712_STATIC | Up | 0.0244803408 |
| GSE19018 | Up | 0.0275180865 |
| GSE19899_A1 | Up | 0.0493269724 |
| GSE19899_A2 | Down | -0.0278550102 |
| PubMed_21979375_A1 | Up | 0.6714283579 |
| PubMed_21979375_A2 | Up | 0.2689724002 |
| GSE35957 | Up | 0.0048840123 |
| GSE36640 | Down | -0.4961801061 |
| GSE54402 | Up | 0.3705962316 |
| GSE9593 | Up | 0.0444946962 |
| GSE43922 | Up | 0.1892904158 |
| GSE24585 | Down | -0.3730802362 |
| GSE37065 | Up | 0.3398335131 |
| GSE28863_A1 | Up | 0.8904891690 |
| GSE28863_A2 | Up | 0.5933709837 |
| GSE28863_A3 | Down | -0.2555763163 |
| GSE28863_A4 | Up | 0.0662322382 |
| GSE48662 | Down | -0.0370045292 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
