HCSGD entry for SOCS6
1. General information
| Official gene symbol | SOCS6 |
|---|---|
| Entrez ID | 9306 |
| Gene full name | suppressor of cytokine signaling 6 |
| Other gene symbols | CIS-4 CIS4 HSPC060 SOCS-4 SOCS-6 SOCS4 SSI4 STAI4 STATI4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001772 | Immunological synapse | IDA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0007259 | JAK-STAT cascade | TAS | biological_process |
| GO:0009968 | Negative regulation of signal transduction | IEA | biological_process |
| GO:0010498 | Proteasomal protein catabolic process | IMP | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0050868 | Negative regulation of T cell activation | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9096664792 | 0.0216106683 | 0.9999902473 | 0.2837565455 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0950994024 |
| GSE13712_SHEAR | Down | -0.2892654389 |
| GSE13712_STATIC | Up | 0.3683290602 |
| GSE19018 | Down | -0.4546747983 |
| GSE19899_A1 | Down | -0.3148359800 |
| GSE19899_A2 | Down | -0.4954845787 |
| PubMed_21979375_A1 | Down | -0.4920090240 |
| PubMed_21979375_A2 | Down | -0.6925225693 |
| GSE35957 | Up | 0.1955711490 |
| GSE36640 | Down | -0.3568966700 |
| GSE54402 | Up | 0.4431505167 |
| GSE9593 | Down | -0.0967525632 |
| GSE43922 | Down | -0.2751457837 |
| GSE24585 | Down | -0.4561156679 |
| GSE37065 | Up | 0.2754565807 |
| GSE28863_A1 | Down | -0.0665586162 |
| GSE28863_A2 | Down | -0.1199110914 |
| GSE28863_A3 | Down | -0.7609399973 |
| GSE28863_A4 | Up | 0.2842537710 |
| GSE48662 | Down | -0.5314126570 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-203a | MIMAT0000264 | MIRT006856 | Luciferase reporter assay | Functional MTI | 22917968 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046359 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
