HCSGD entry for CER1

1. General information

Official gene symbolCER1
Entrez ID9350
Gene full namecerberus 1, DAN family BMP antagonist
Other gene symbolsDAND4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001657Ureteric bud developmentISSbiological_process
GO:0003419Growth plate cartilage chondrocyte proliferationISSbiological_process
GO:0005125Cytokine activityIEAmolecular_function
GO:0005576Extracellular regionISS TAScellular_component
GO:0005615Extracellular spaceISScellular_component
GO:0007369GastrulationISSbiological_process
GO:0007399Nervous system developmentIMPbiological_process
GO:0008285Negative regulation of cell proliferationISSbiological_process
GO:0009948Anterior/posterior axis specificationISSbiological_process
GO:0009952Anterior/posterior pattern specificationISSbiological_process
GO:0016015Morphogen activityIDAmolecular_function
GO:0023019Signal transduction involved in regulation of gene expressionISSbiological_process
GO:0030178Negative regulation of Wnt signaling pathwayISSbiological_process
GO:0030282Bone mineralizationIMPbiological_process
GO:0030509BMP signaling pathwayTASbiological_process
GO:0030514Negative regulation of BMP signaling pathwayISSbiological_process
GO:0032926Negative regulation of activin receptor signaling pathwayIDA ISSbiological_process
GO:0035582Sequestering of BMP in extracellular matrixIDA ISSbiological_process
GO:0036122BMP bindingIDAmolecular_function
GO:0042074Cell migration involved in gastrulationISSbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0048263Determination of dorsal identityIMPbiological_process
GO:0071773Cellular response to BMP stimulusISSbiological_process
GO:2000381Negative regulation of mesoderm developmentIMP ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35259949090.86594029860.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0547993387
GSE13712_SHEARUp0.1358848621
GSE13712_STATICDown-0.0132819672
GSE19018Up0.2539737730
GSE19899_A1Up0.2781640955
GSE19899_A2Down-0.0348398149
PubMed_21979375_A1Down-0.1978599089
PubMed_21979375_A2Up0.2778997118
GSE35957Up0.0608544093
GSE36640Up0.1648027915
GSE54402Up0.0054953631
GSE9593Up0.0296198802
GSE43922Up0.0125365483
GSE24585Up0.2457541652
GSE37065Down-0.0955775085
GSE28863_A1Down-0.0425781346
GSE28863_A2Down-0.1895354418
GSE28863_A3Up0.1398884399
GSE28863_A4Down-0.0258830925
GSE48662Up0.0391870469

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.