HCSGD entry for TBCK
1. General information
| Official gene symbol | TBCK |
|---|---|
| Entrez ID | 93627 |
| Gene full name | TBC1 domain containing kinase |
| Other gene symbols | TBCKL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA RCA | molecular_function |
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA RCA | molecular_function |
| GO:0006468 | Protein phosphorylation | RCA | biological_process |
| GO:0008152 | Metabolic process | RCA | biological_process |
| GO:0016310 | Phosphorylation | RCA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9089128453 | 0.0019079860 | 0.9999902473 | 0.0845028523 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3257289718 |
| GSE13712_SHEAR | Down | -0.4747765739 |
| GSE13712_STATIC | Down | -0.0025941137 |
| GSE19018 | Up | 0.1634583664 |
| GSE19899_A1 | Down | -1.3533163120 |
| GSE19899_A2 | Down | -1.0558655743 |
| PubMed_21979375_A1 | Down | -1.7832927710 |
| PubMed_21979375_A2 | Down | -1.5925404269 |
| GSE35957 | Down | -0.0910591564 |
| GSE36640 | Up | 0.8414222433 |
| GSE54402 | Down | -0.7360687987 |
| GSE9593 | Up | 0.0069348478 |
| GSE43922 | Down | -1.0777180023 |
| GSE24585 | Up | 0.7679073054 |
| GSE37065 | Down | -0.2018324968 |
| GSE28863_A1 | Down | -0.0909777601 |
| GSE28863_A2 | Down | -0.3887209909 |
| GSE28863_A3 | Down | -0.9064816615 |
| GSE28863_A4 | Down | -0.3060158543 |
| GSE48662 | Up | 0.0872541683 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018768 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
