HCSGD entry for NRXN3
1. General information
| Official gene symbol | NRXN3 |
|---|---|
| Entrez ID | 9369 |
| Gene full name | neurexin 3 |
| Other gene symbols | C14orf60 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | ISS | biological_process |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005246 | Calcium channel regulator activity | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007269 | Neurotransmitter secretion | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007416 | Synapse assembly | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051965 | Positive regulation of synapse assembly | IEA | biological_process |
| GO:0090129 | Positive regulation of synapse maturation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9005945671 | 0.0024090042 | 0.9999902473 | 0.0953954887 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4786091553 |
| GSE13712_SHEAR | Up | 0.0957205841 |
| GSE13712_STATIC | Up | 0.3176932524 |
| GSE19018 | Down | -0.5510793743 |
| GSE19899_A1 | Down | -0.4019943793 |
| GSE19899_A2 | Down | -2.4440238958 |
| PubMed_21979375_A1 | Down | -1.6006348585 |
| PubMed_21979375_A2 | Down | -2.8476156526 |
| GSE35957 | Up | 0.0143582471 |
| GSE36640 | Up | 0.2870334534 |
| GSE54402 | Down | -0.7822632376 |
| GSE9593 | Down | -0.0890080028 |
| GSE43922 | Down | -1.7933530330 |
| GSE24585 | Down | -0.3186428690 |
| GSE37065 | Down | -0.0417346765 |
| GSE28863_A1 | Down | -0.0047028080 |
| GSE28863_A2 | Down | -0.0183833492 |
| GSE28863_A3 | Up | 0.2044936465 |
| GSE28863_A4 | Up | 0.1273767459 |
| GSE48662 | Up | 0.0305635340 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016059 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049473 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
