HCSGD entry for LPXN

1. General information

Official gene symbolLPXN
Entrez ID9404
Gene full nameleupaxin
Other gene symbolsLDPL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002102PodosomeIDAcellular_component
GO:0003712Transcription cofactor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006461Protein complex assemblyTASbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007162Negative regulation of cell adhesionIDAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0033628Regulation of cell adhesion mediated by integrinIEAbiological_process
GO:0042995Cell projectionIEAcellular_component
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050859Negative regulation of B cell receptor signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00004720190.98675185970.01889130431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.2898848773
GSE13712_SHEARUp1.5484219596
GSE13712_STATICUp1.2671359331
GSE19018Up0.6402870159
GSE19899_A1Up1.8674319219
GSE19899_A2Up1.5906178085
PubMed_21979375_A1Up1.3875404163
PubMed_21979375_A2Up1.3683913899
GSE35957Up0.0651672577
GSE36640Up1.1390027782
GSE54402Up1.6026435812
GSE9593Down-0.1189569329
GSE43922Up1.5712846401
GSE24585Up0.6218057531
GSE37065Up0.8118079400
GSE28863_A1Down-0.5440416542
GSE28863_A2Up0.5227522136
GSE28863_A3Up0.1011115109
GSE28863_A4Up0.2821005079
GSE48662Down-0.8966106128

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-9-5pMIMAT0000441MIRT021415MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.