HCSGD entry for MED23

1. General information

Official gene symbolMED23
Entrez ID9439
Gene full namemediator complex subunit 23
Other gene symbolsARC130 CRSP130 CRSP133 CRSP3 DRIP130 MRT18 SUR-2 SUR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016592Mediator complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61430617000.27940891300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0577306074
GSE13712_SHEARUp0.0084221129
GSE13712_STATICUp0.0074150494
GSE19018Down-0.1024722428
GSE19899_A1Down-0.1271127637
GSE19899_A2Up0.1703622875
PubMed_21979375_A1Up0.0561125283
PubMed_21979375_A2Up0.5050192116
GSE35957Up0.0544833654
GSE36640Up0.1079731068
GSE54402Down-0.1414649702
GSE9593Down-0.0854344707
GSE43922Up0.0888704867
GSE24585Up0.1003469993
GSE37065Down-0.0293472958
GSE28863_A1Up0.0923316601
GSE28863_A2Up0.4808135824
GSE28863_A3Down-0.9805080913
GSE28863_A4Down-0.3422249067
GSE48662Down-0.2742227124

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029125MicroarrayFunctional MTI (Weak)19088304
hsa-miR-320aMIMAT0000510MIRT044390CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.