HCSGD entry for RASAL2


1. General information

Official gene symbolRASAL2
Entrez ID9462
Gene full nameRAS protein activator like 2
Other gene symbolsNGAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005096GTPase activator activityIEAmolecular_function
GO:0005099Ras GTPase activator activityIBAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0031235Intrinsic component of the cytoplasmic side of the plasma membraneIBAcellular_component
GO:0032320Positive regulation of Ras GTPase activityIBAbiological_process
GO:0046580Negative regulation of Ras protein signal transductionIBAbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52827502370.42455915810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0923850116
GSE13712_SHEARUp0.0246132110
GSE13712_STATICDown-0.0597254497
GSE19018Up0.0906180180
GSE19899_A1Down-0.0589831644
GSE19899_A2Down-0.0187857097
PubMed_21979375_A1Down-0.5037872888
PubMed_21979375_A2Up0.1937776811
GSE35957Up0.2523367103
GSE36640Up0.0878872470
GSE54402Down-0.1268377180
GSE9593Up0.3090229819
GSE43922Down-0.0276190367
GSE24585Down-0.0066878763
GSE37065Up0.1897070657
GSE28863_A1Up0.3044452363
GSE28863_A2Up0.6523224494
GSE28863_A3Down-0.5777916756
GSE28863_A4Down-0.2746768699
GSE48662Down-0.0576479451

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027468MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT029026MicroarrayFunctional MTI (Weak)19088304
hsa-miR-15a-3pMIMAT0004488MIRT038984CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT045969CLASHFunctional MTI (Weak)23622248
hsa-miR-99a-5pMIMAT0000097MIRT048603CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048987CLASH//qRT-PCRFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.