HCSGD entry for GABBR2

1. General information

Official gene symbolGABBR2
Entrez ID9568
Gene full namegamma-aminobutyric acid (GABA) B receptor, 2
Other gene symbolsGABABR2 GPR51 GPRC3B HG20 HRIHFB2099
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004965G-protein coupled GABA receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007194Negative regulation of adenylate cyclase activityTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIDAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0038039G-protein coupled receptor heterodimeric complexIPIcellular_component
GO:0043005Neuron projectionIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08724417010.03830994260.61979859650.3682830898

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4828163292
GSE13712_SHEARDown-1.5380012919
GSE13712_STATICUp0.0746669456
GSE19018Up0.4336700700
GSE19899_A1Down-0.8472580327
GSE19899_A2Down-0.3861288036
PubMed_21979375_A1Down-0.1474870525
PubMed_21979375_A2Up0.1996520260
GSE35957Up0.8262160500
GSE36640Up0.7583138573
GSE54402Down-0.7441931095
GSE9593Up0.0372334365
GSE43922Down-0.0028165909
GSE24585Down-0.3032044748
GSE37065Up0.5563140505
GSE28863_A1Down-0.5033755819
GSE28863_A2Up0.0482109539
GSE28863_A3Up0.4868559373
GSE28863_A4Down-0.2115953168
GSE48662Down-0.4222556651

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

SGS742DB05010 -
ArbaclofenDB08891 -
Arbaclofen PlacarbilDB08892 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022745MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.