HCSGD entry for CDC42BPB
1. General information
| Official gene symbol | CDC42BPB |
|---|---|
| Entrez ID | 9578 |
| Gene full name | CDC42 binding protein kinase beta (DMPK-like) |
| Other gene symbols | MRCKB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | ISS | molecular_function |
| GO:0004672 | Protein kinase activity | IDA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | ISS | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA ISS | biological_process |
| GO:0007010 | Cytoskeleton organization | TAS | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016477 | Cell migration | IMP | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
| GO:0031032 | Actomyosin structure organization | IMP | biological_process |
| GO:0031252 | Cell leading edge | ISS | cellular_component |
| GO:0031532 | Actin cytoskeleton reorganization | IEA ISS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0042641 | Actomyosin | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0091198131 | 0.9901776490 | 0.2444425662 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1606991373 |
| GSE13712_SHEAR | Up | 0.0102455889 |
| GSE13712_STATIC | Down | -0.0987745827 |
| GSE19018 | Up | 0.0697370423 |
| GSE19899_A1 | Up | 0.1646100978 |
| GSE19899_A2 | Up | 0.4727478466 |
| PubMed_21979375_A1 | Up | 1.6406722611 |
| PubMed_21979375_A2 | Up | 1.4351532140 |
| GSE35957 | Up | 0.3398498494 |
| GSE36640 | Up | 0.3400566909 |
| GSE54402 | Up | 0.2712663180 |
| GSE9593 | Up | 0.2311905609 |
| GSE43922 | Up | 0.2367077291 |
| GSE24585 | Up | 0.1332974996 |
| GSE37065 | Down | -0.1281958028 |
| GSE28863_A1 | Up | 0.5547753184 |
| GSE28863_A2 | Up | 0.4890453694 |
| GSE28863_A3 | Up | 0.4376675010 |
| GSE28863_A4 | Up | 0.1353483463 |
| GSE48662 | Up | 0.4613790558 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020532 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023484 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
