HCSGD entry for IQCB1
1. General information
| Official gene symbol | IQCB1 |
|---|---|
| Entrez ID | 9657 |
| Gene full name | IQ motif containing B1 |
| Other gene symbols | NPHP5 PIQ SLSN5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001750 | Photoreceptor outer segment | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0032391 | Photoreceptor connecting cilium | IDA IEA | cellular_component |
| GO:0042384 | Cilium assembly | IEA ISS | biological_process |
| GO:0045494 | Photoreceptor cell maintenance | IMP | biological_process |
| GO:0048496 | Maintenance of organ identity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9537074959 | 0.0148096843 | 0.9999902473 | 0.2396723483 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0366874498 |
| GSE13712_SHEAR | Up | 0.2967447621 |
| GSE13712_STATIC | Up | 0.2217905562 |
| GSE19018 | Down | -0.3170131481 |
| GSE19899_A1 | Down | -0.3341202761 |
| GSE19899_A2 | Down | -1.0581279552 |
| PubMed_21979375_A1 | Down | -0.5912370062 |
| PubMed_21979375_A2 | Down | -1.1271762690 |
| GSE35957 | Down | -0.4248482595 |
| GSE36640 | Down | -0.7535287580 |
| GSE54402 | Down | -0.2134664654 |
| GSE9593 | Down | -0.0521427176 |
| GSE43922 | Down | -0.3924900584 |
| GSE24585 | Down | -0.4700178666 |
| GSE37065 | Down | -0.0574020724 |
| GSE28863_A1 | Up | 0.1600019908 |
| GSE28863_A2 | Up | 0.3095946422 |
| GSE28863_A3 | Down | -0.4146876687 |
| GSE28863_A4 | Up | 0.0116102463 |
| GSE48662 | Down | -0.3130331939 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027674 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030516 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047676 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
