HCSGD entry for KNTC1
1. General information
| Official gene symbol | KNTC1 |
|---|---|
| Entrez ID | 9735 |
| Gene full name | kinetochore associated 1 |
| Other gene symbols | ROD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005828 | Kinetochore microtubule | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006461 | Protein complex assembly | NAS | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007093 | Mitotic cell cycle checkpoint | IDA | biological_process |
| GO:0007096 | Regulation of exit from mitosis | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7962968846 | 0.0007067171 | 0.9999902473 | 0.0501388140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2342028102 |
| GSE13712_SHEAR | Down | -0.2640484718 |
| GSE13712_STATIC | Down | -0.3804540485 |
| GSE19018 | Down | -0.2537300678 |
| GSE19899_A1 | Down | -0.2159107309 |
| GSE19899_A2 | Down | -2.5566851764 |
| PubMed_21979375_A1 | Down | -1.4934492020 |
| PubMed_21979375_A2 | Down | -1.3969343081 |
| GSE35957 | Down | -1.9721369712 |
| GSE36640 | Down | -2.8466625886 |
| GSE54402 | Down | -0.1790306909 |
| GSE9593 | Down | -1.0053899476 |
| GSE43922 | Down | -1.1116753272 |
| GSE24585 | Up | 0.6257713082 |
| GSE37065 | Down | -0.2768954957 |
| GSE28863_A1 | Up | 0.0250330032 |
| GSE28863_A2 | Up | 1.3973183994 |
| GSE28863_A3 | Down | -0.6051750950 |
| GSE28863_A4 | Up | 0.3205210661 |
| GSE48662 | Down | -1.1893961798 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016317 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-484 | MIMAT0002174 | MIRT041835 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045471 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047167 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
