HCSGD entry for ARHGAP32
1. General information
| Official gene symbol | ARHGAP32 |
|---|---|
| Entrez ID | 9743 |
| Gene full name | Rho GTPase activating protein 32 |
| Other gene symbols | GC-GAP GRIT PX-RICS RICS p200RhoGAP p250GAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0043197 | Dendritic spine | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7373289731 | 0.0157534402 | 0.9999902473 | 0.2454981054 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1731428698 |
| GSE13712_SHEAR | Down | -0.3916126591 |
| GSE13712_STATIC | Down | -0.2313743759 |
| GSE19018 | Up | 0.1160082937 |
| GSE19899_A1 | Down | -0.1237020142 |
| GSE19899_A2 | Down | -0.9998653014 |
| PubMed_21979375_A1 | Down | -0.8905950985 |
| PubMed_21979375_A2 | Down | -0.6274430565 |
| GSE35957 | Down | -0.2226317278 |
| GSE36640 | Down | -1.1684301701 |
| GSE54402 | Up | 0.3014183488 |
| GSE9593 | Down | -0.0431430790 |
| GSE43922 | Down | -0.5069418557 |
| GSE24585 | Down | -0.1927277378 |
| GSE37065 | Down | -0.0322853081 |
| GSE28863_A1 | Up | 1.1959493652 |
| GSE28863_A2 | Up | 0.8044335023 |
| GSE28863_A3 | Down | -0.4621499471 |
| GSE28863_A4 | Down | -0.1349939633 |
| GSE48662 | Down | -0.2411266758 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT003926 | qRT-PCR | Functional MTI (Weak) | 18082412 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT003926 | Luciferase reporter assay//Western blot | Functional MTI | 18577589 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT003926 | Luciferase reporter assay | Functional MTI | 19850129 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038109 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047063 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048798 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | NA | hsa-miR-132 | 18577589 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
