HCSGD entry for ARNT2
1. General information
| Official gene symbol | ARNT2 |
|---|---|
| Entrez ID | 9915 |
| Gene full name | aryl-hydrocarbon receptor nuclear translocator 2 |
| Other gene symbols | bHLHe1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IDA IEA | biological_process |
| GO:0001701 | In utero embryonic development | IEA ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA ISS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0007417 | Central nervous system development | IEA ISS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0017162 | Aryl hydrocarbon receptor binding | IEA ISS | molecular_function |
| GO:0032355 | Response to estradiol | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA IPI ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7453007143 | 0.0123637932 | 0.9999902473 | 0.2194385705 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6682310560 |
| GSE13712_SHEAR | Up | 0.0423692968 |
| GSE13712_STATIC | Up | 0.0735574613 |
| GSE19018 | Down | -0.3359375387 |
| GSE19899_A1 | Down | -1.0910090935 |
| GSE19899_A2 | Down | -0.6581751450 |
| PubMed_21979375_A1 | Down | -1.6478880390 |
| PubMed_21979375_A2 | Down | -1.0666860884 |
| GSE35957 | Up | 0.9436188642 |
| GSE36640 | Down | -1.3077035271 |
| GSE54402 | Up | 0.2154216827 |
| GSE9593 | Up | 0.2778758485 |
| GSE43922 | Down | -0.9621678017 |
| GSE24585 | Up | 0.1885567911 |
| GSE37065 | Down | -0.2157754067 |
| GSE28863_A1 | Down | -0.0397273371 |
| GSE28863_A2 | Up | 0.7709209165 |
| GSE28863_A3 | Down | -0.0452537224 |
| GSE28863_A4 | Down | -0.0502369104 |
| GSE48662 | Down | -0.1678072146 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029615 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051426 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
