HCSGD entry for PPP4R1
1. General information
| Official gene symbol | PPP4R1 |
|---|---|
| Entrez ID | 9989 |
| Gene full name | protein phosphatase 4, regulatory subunit 1 |
| Other gene symbols | MEG1 PP4(Rmeg) PP4R1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004721 | Phosphoprotein phosphatase activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006468 | Protein phosphorylation | ISS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0016311 | Dephosphorylation | ISS | biological_process |
| GO:0030289 | Protein phosphatase 4 complex | ISS | cellular_component |
| GO:0030362 | Protein phosphatase type 4 regulator activity | NAS | molecular_function |
| GO:0050790 | Regulation of catalytic activity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9872327875 | 0.0301524752 | 0.9999902473 | 0.3279030140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1564462958 |
| GSE13712_SHEAR | Down | -0.0436387685 |
| GSE13712_STATIC | Down | -0.0267146524 |
| GSE19018 | Up | 0.0394649600 |
| GSE19899_A1 | Down | -0.9811756714 |
| GSE19899_A2 | Down | -0.3576340199 |
| PubMed_21979375_A1 | Up | 0.2203954306 |
| PubMed_21979375_A2 | Down | -0.0123781436 |
| GSE35957 | Up | 0.1924460485 |
| GSE36640 | Down | -0.5840598430 |
| GSE54402 | Down | -0.1017190299 |
| GSE9593 | Down | -0.1646874371 |
| GSE43922 | Down | -0.3846318173 |
| GSE24585 | Down | -0.2539065053 |
| GSE37065 | Down | -0.0935312420 |
| GSE28863_A1 | Down | -0.2071938283 |
| GSE28863_A2 | Down | -0.0612730986 |
| GSE28863_A3 | Down | -0.7093626670 |
| GSE28863_A4 | Up | 0.0429122882 |
| GSE48662 | Down | -0.4829902430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-101-3p | MIMAT0000099 | MIRT027240 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045435 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
