HCSGD entry for TANK

1. General information

Official gene symbolTANK
Entrez ID10010
Gene full nameTRAF family member-associated NFKB activator
Other gene symbolsI-TRAF ITRAF TRAF2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007249I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0045087Innate immune responseTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06337467800.93448001980.54299638671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0451308595
GSE13712_SHEARUp0.5113835810
GSE13712_STATICUp0.3726937987
GSE19018Down-0.1624912441
GSE19899_A1Up0.3533824339
GSE19899_A2Up0.1886819364
PubMed_21979375_A1Up0.9692654790
PubMed_21979375_A2Down-0.0085553520
GSE35957Up0.0506626101
GSE36640Up0.1103427645
GSE54402Up0.4141959486
GSE9593Up0.1438036864
GSE43922Up0.2445881921
GSE24585Up0.5206009527
GSE37065Up0.0738884306
GSE28863_A1Up0.1297609523
GSE28863_A2Up0.0664459888
GSE28863_A3Down-0.4654420497
GSE28863_A4Down-0.2122503025
GSE48662Down-0.1764152588

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.