HCSGD entry for TANK
1. General information
| Official gene symbol | TANK |
|---|---|
| Entrez ID | 10010 |
| Gene full name | TRAF family member-associated NFKB activator |
| Other gene symbols | I-TRAF ITRAF TRAF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IEA | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0633746780 | 0.9344800198 | 0.5429963867 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0451308595 |
| GSE13712_SHEAR | Up | 0.5113835810 |
| GSE13712_STATIC | Up | 0.3726937987 |
| GSE19018 | Down | -0.1624912441 |
| GSE19899_A1 | Up | 0.3533824339 |
| GSE19899_A2 | Up | 0.1886819364 |
| PubMed_21979375_A1 | Up | 0.9692654790 |
| PubMed_21979375_A2 | Down | -0.0085553520 |
| GSE35957 | Up | 0.0506626101 |
| GSE36640 | Up | 0.1103427645 |
| GSE54402 | Up | 0.4141959486 |
| GSE9593 | Up | 0.1438036864 |
| GSE43922 | Up | 0.2445881921 |
| GSE24585 | Up | 0.5206009527 |
| GSE37065 | Up | 0.0738884306 |
| GSE28863_A1 | Up | 0.1297609523 |
| GSE28863_A2 | Up | 0.0664459888 |
| GSE28863_A3 | Down | -0.4654420497 |
| GSE28863_A4 | Down | -0.2122503025 |
| GSE48662 | Down | -0.1764152588 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
