HCSGD entry for CD24

1. General information

Official gene symbolCD24
Entrez ID100133941
Gene full nameCD24 molecule
Other gene symbolsCD24A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEPbiological_process
GO:0001775Cell activationIDAbiological_process
GO:0001959Regulation of cytokine-mediated signaling pathwayISSbiological_process
GO:0002237Response to molecule of bacterial originISSbiological_process
GO:0002768Immune response-regulating cell surface receptor signaling pathwayICbiological_process
GO:0004871Signal transducer activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016055Wnt signaling pathwayNASbiological_process
GO:0016337Cell-cell adhesionNASbiological_process
GO:0016477Cell migrationISSbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030296Protein tyrosine kinase activator activityIDAmolecular_function
GO:0030856Regulation of epithelial cell differentiationNASbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0031295T cell costimulationIDAbiological_process
GO:0032597B cell receptor transport into membrane raftIDAbiological_process
GO:0032600Chemokine receptor transport out of membrane raftISSbiological_process
GO:0032913Negative regulation of transforming growth factor beta3 productionIMPbiological_process
GO:0042104Positive regulation of activated T cell proliferationIDAbiological_process
GO:0042325Regulation of phosphorylationIDAbiological_process
GO:0042632Cholesterol homeostasisISSbiological_process
GO:0043406Positive regulation of MAP kinase activityIDAbiological_process
GO:0043408Regulation of MAPK cascadeIDAbiological_process
GO:0043627Response to estrogenIEPbiological_process
GO:0045121Membrane raftIDAcellular_component
GO:0045730Respiratory burstIDAbiological_process
GO:0061098Positive regulation of protein tyrosine kinase activityIDAbiological_process
GO:0072112Glomerular visceral epithelial cell differentiationIMPbiological_process
GO:0072139Glomerular parietal epithelial cell differentiationIMPbiological_process
GO:0097193Intrinsic apoptotic signaling pathwayNASbiological_process
GO:2000768Positive regulation of nephron tubule epithelial cell differentiationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01557221230.01080388280.30957416920.2059152788

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up2.3653987356
GSE13712_SHEARUp0.0677223732
GSE13712_STATICDown-0.2325166332
GSE19018Down-0.0445535585
GSE19899_A1Up0.1826160977
GSE19899_A2Up0.7082149090
PubMed_21979375_A1Up0.5350597327
PubMed_21979375_A2Up0.8588985940
GSE35957Down-1.4393902271
GSE36640Up0.3046966616
GSE54402Up0.6337984127
GSE9593Down-0.6166627908
GSE43922Up0.5004841926
GSE24585Up0.3105942090
GSE37065Up1.1836507413
GSE28863_A1Down-2.6675142757
GSE28863_A2Down-2.7849915642
GSE28863_A3Down-0.0676052562
GSE28863_A4Down-0.4926680421
GSE48662Up0.0658633123

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT002501MicroarrayFunctional MTI (Weak)15685193
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

20585577The SCP cells produced CD24+ or ER+ luminal-like and ASMA+ myoepithelial-like progeny, in addition to CD44+ stem/progenitor-like cells
19751512Analysis of surface markers during long term tumor culture of primary HBCEC (more than 476d) demonstrated a prominent expression of CD24, CD44 and MUC1 (CD227)
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