HCSGD entry for CD24
1. General information
| Official gene symbol | CD24 |
|---|---|
| Entrez ID | 100133941 |
| Gene full name | CD24 molecule |
| Other gene symbols | CD24A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEP | biological_process |
| GO:0001775 | Cell activation | IDA | biological_process |
| GO:0001959 | Regulation of cytokine-mediated signaling pathway | ISS | biological_process |
| GO:0002237 | Response to molecule of bacterial origin | ISS | biological_process |
| GO:0002768 | Immune response-regulating cell surface receptor signaling pathway | IC | biological_process |
| GO:0004871 | Signal transducer activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IDA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016055 | Wnt signaling pathway | NAS | biological_process |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0016477 | Cell migration | ISS | biological_process |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0030296 | Protein tyrosine kinase activator activity | IDA | molecular_function |
| GO:0030856 | Regulation of epithelial cell differentiation | NAS | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0031295 | T cell costimulation | IDA | biological_process |
| GO:0032597 | B cell receptor transport into membrane raft | IDA | biological_process |
| GO:0032600 | Chemokine receptor transport out of membrane raft | ISS | biological_process |
| GO:0032913 | Negative regulation of transforming growth factor beta3 production | IMP | biological_process |
| GO:0042104 | Positive regulation of activated T cell proliferation | IDA | biological_process |
| GO:0042325 | Regulation of phosphorylation | IDA | biological_process |
| GO:0042632 | Cholesterol homeostasis | ISS | biological_process |
| GO:0043406 | Positive regulation of MAP kinase activity | IDA | biological_process |
| GO:0043408 | Regulation of MAPK cascade | IDA | biological_process |
| GO:0043627 | Response to estrogen | IEP | biological_process |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0045730 | Respiratory burst | IDA | biological_process |
| GO:0061098 | Positive regulation of protein tyrosine kinase activity | IDA | biological_process |
| GO:0072112 | Glomerular visceral epithelial cell differentiation | IMP | biological_process |
| GO:0072139 | Glomerular parietal epithelial cell differentiation | IMP | biological_process |
| GO:0097193 | Intrinsic apoptotic signaling pathway | NAS | biological_process |
| GO:2000768 | Positive regulation of nephron tubule epithelial cell differentiation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0155722123 | 0.0108038828 | 0.3095741692 | 0.2059152788 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 2.3653987356 |
| GSE13712_SHEAR | Up | 0.0677223732 |
| GSE13712_STATIC | Down | -0.2325166332 |
| GSE19018 | Down | -0.0445535585 |
| GSE19899_A1 | Up | 0.1826160977 |
| GSE19899_A2 | Up | 0.7082149090 |
| PubMed_21979375_A1 | Up | 0.5350597327 |
| PubMed_21979375_A2 | Up | 0.8588985940 |
| GSE35957 | Down | -1.4393902271 |
| GSE36640 | Up | 0.3046966616 |
| GSE54402 | Up | 0.6337984127 |
| GSE9593 | Down | -0.6166627908 |
| GSE43922 | Up | 0.5004841926 |
| GSE24585 | Up | 0.3105942090 |
| GSE37065 | Up | 1.1836507413 |
| GSE28863_A1 | Down | -2.6675142757 |
| GSE28863_A2 | Down | -2.7849915642 |
| GSE28863_A3 | Down | -0.0676052562 |
| GSE28863_A4 | Down | -0.4926680421 |
| GSE48662 | Up | 0.0658633123 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002501 | Microarray | Functional MTI (Weak) | 15685193 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20585577 | The SCP cells produced CD24+ or ER+ luminal-like and ASMA+ myoepithelial-like progeny, in addition to CD44+ stem/progenitor-like cells |
| 19751512 | Analysis of surface markers during long term tumor culture of primary HBCEC (more than 476d) demonstrated a prominent expression of CD24, CD44 and MUC1 (CD227) |
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