HCSGD entry for TDRKH
1. General information
| Official gene symbol | TDRKH |
|---|---|
| Entrez ID | 11022 |
| Gene full name | tudor and KH domain containing |
| Other gene symbols | TDRD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA ISS | cellular_component |
| GO:0007140 | Male meiosis | IEA ISS | biological_process |
| GO:0007283 | Spermatogenesis | IEA ISS | biological_process |
| GO:0009566 | Fertilization | IEA ISS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0031047 | Gene silencing by RNA | IEA | biological_process |
| GO:0034587 | PiRNA metabolic process | IEA ISS | biological_process |
| GO:0043046 | DNA methylation involved in gamete generation | IEA ISS | biological_process |
| GO:0071546 | Pi-body | IEA ISS | cellular_component |
| GO:0071547 | PiP-body | IEA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2035170054 | 0.9560636488 | 0.8704754873 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0115299588 |
| GSE13712_SHEAR | Down | -0.1519761134 |
| GSE13712_STATIC | Down | -0.0555299678 |
| GSE19018 | Up | 0.1520023832 |
| GSE19899_A1 | Up | 0.1519598904 |
| GSE19899_A2 | Up | 0.2099912952 |
| PubMed_21979375_A1 | Down | -0.0416399948 |
| PubMed_21979375_A2 | Up | 0.1507164360 |
| GSE35957 | Down | -0.0066780688 |
| GSE36640 | Up | 0.7488053271 |
| GSE54402 | Down | -0.0120075632 |
| GSE9593 | Down | -0.0829770121 |
| GSE43922 | Up | 0.1755074617 |
| GSE24585 | Up | 0.2735572064 |
| GSE37065 | Up | 0.0394283378 |
| GSE28863_A1 | Down | -0.1110225760 |
| GSE28863_A2 | Up | 0.5894543718 |
| GSE28863_A3 | Up | 0.1663189599 |
| GSE28863_A4 | Up | 0.0463678502 |
| GSE48662 | Down | -0.0952159207 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037409 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038037 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17415412 | Ewing sarcoma gene EWS encodes a putative RNA-binding protein with proposed roles in transcription and splicing, but its physiological role in vivo remains undefined |
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