HCSGD entry for TDRKH


1. General information

Official gene symbolTDRKH
Entrez ID11022
Gene full nametudor and KH domain containing
Other gene symbolsTDRD2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003723RNA bindingIEAmolecular_function
GO:0005739MitochondrionIEA ISScellular_component
GO:0007140Male meiosisIEA ISSbiological_process
GO:0007283SpermatogenesisIEA ISSbiological_process
GO:0009566FertilizationIEA ISSbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0031047Gene silencing by RNAIEAbiological_process
GO:0034587PiRNA metabolic processIEA ISSbiological_process
GO:0043046DNA methylation involved in gamete generationIEA ISSbiological_process
GO:0071546Pi-bodyIEA ISScellular_component
GO:0071547PiP-bodyIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20351700540.95606364880.87047548731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0115299588
GSE13712_SHEARDown-0.1519761134
GSE13712_STATICDown-0.0555299678
GSE19018Up0.1520023832
GSE19899_A1Up0.1519598904
GSE19899_A2Up0.2099912952
PubMed_21979375_A1Down-0.0416399948
PubMed_21979375_A2Up0.1507164360
GSE35957Down-0.0066780688
GSE36640Up0.7488053271
GSE54402Down-0.0120075632
GSE9593Down-0.0829770121
GSE43922Up0.1755074617
GSE24585Up0.2735572064
GSE37065Up0.0394283378
GSE28863_A1Down-0.1110225760
GSE28863_A2Up0.5894543718
GSE28863_A3Up0.1663189599
GSE28863_A4Up0.0463678502
GSE48662Down-0.0952159207

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037409CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038037CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

17415412Ewing sarcoma gene EWS encodes a putative RNA-binding protein with proposed roles in transcription and splicing, but its physiological role in vivo remains undefined
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