HCSGD entry for KAT7

1. General information

Official gene symbolKAT7
Entrez ID11143
Gene full nameK(lysine) acetyltransferase 7
Other gene symbolsHBO1 HBOA MYST2 ZC2HC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000123Histone acetyltransferase complexIDAcellular_component
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0004402Histone acetyltransferase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006260DNA replicationIDAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016747Transferase activity, transferring acyl groups other than amino-acyl groupsIEAmolecular_function
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0043981Histone H4-K5 acetylationIDAbiological_process
GO:0043982Histone H4-K8 acetylationIDAbiological_process
GO:0043983Histone H4-K12 acetylationIDAbiological_process
GO:0043984Histone H4-K16 acetylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40524769200.19321377610.99999024730.8521829759

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0832029383
GSE13712_SHEARDown-0.9199881714
GSE13712_STATICDown-0.3649499201
GSE19018Up0.1952330490
GSE19899_A1Down-0.1458825104
GSE19899_A2Down-0.4393853385
PubMed_21979375_A1Up0.3803128258
PubMed_21979375_A2Up0.4614154387
GSE35957Down-0.3588648384
GSE36640Down-0.5716579984
GSE54402Up0.1445520904
GSE9593Down-0.1422019599
GSE43922Down-0.1133408281
GSE24585Up0.3150334462
GSE37065Up0.0782607327
GSE28863_A1Up0.5486765377
GSE28863_A2Up0.4119674354
GSE28863_A3Down-0.2003529515
GSE28863_A4Down-0.0342026211
GSE48662Down-0.2604845844

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT044356CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.