HCSGD entry for KAT7

1. General information

Official gene symbolKAT7
Entrez ID11143
Gene full nameK(lysine) acetyltransferase 7
Other gene symbolsHBO1 HBOA MYST2 ZC2HC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000123Histone acetyltransferase complexIDAcellular_component
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0004402Histone acetyltransferase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006260DNA replicationIDAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016747Transferase activity, transferring acyl groups other than amino-acyl groupsIEAmolecular_function
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0043981Histone H4-K5 acetylationIDAbiological_process
GO:0043982Histone H4-K8 acetylationIDAbiological_process
GO:0043983Histone H4-K12 acetylationIDAbiological_process
GO:0043984Histone H4-K16 acetylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40524769200.19321377610.99999024730.8521829759

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0832029383
GSE13712_SHEARDown-0.9199881714
GSE13712_STATICDown-0.3649499201
GSE19018Up0.1952330490
GSE19899_A1Down-0.1458825104
GSE19899_A2Down-0.4393853385
PubMed_21979375_A1Up0.3803128258
PubMed_21979375_A2Up0.4614154387
GSE35957Down-0.3588648384
GSE36640Down-0.5716579984
GSE54402Up0.1445520904
GSE9593Down-0.1422019599
GSE43922Down-0.1133408281
GSE24585Up0.3150334462
GSE37065Up0.0782607327
GSE28863_A1Up0.5486765377
GSE28863_A2Up0.4119674354
GSE28863_A3Down-0.2003529515
GSE28863_A4Down-0.0342026211
GSE48662Down-0.2604845844

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT044356CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.