HCSGD entry for TPH2

1. General information

Official gene symbolTPH2
Entrez ID121278
Gene full nametryptophan hydroxylase 2
Other gene symbolsADHD7 NTPH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004510Tryptophan 5-monooxygenase activityIEAmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0007623Circadian rhythmIEAbiological_process
GO:0009072Aromatic amino acid family metabolic processIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0016597Amino acid bindingIEAmolecular_function
GO:0031667Response to nutrient levelsIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042427Serotonin biosynthetic processIEAbiological_process
GO:0043005Neuron projectionIEAcellular_component
GO:0043627Response to estrogenIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046219Indolalkylamine biosynthetic processTASbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051592Response to calcium ionIEAbiological_process
GO:0071285Cellular response to lithium ionIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35396417310.94380740470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0141011112
GSE13712_SHEARDown-0.0264770465
GSE13712_STATICDown-0.0089952463
GSE19018Up0.2141619871
GSE19899_A1Up0.2012768793
GSE19899_A2Up0.4040248068
PubMed_21979375_A1Down-0.0002214376
PubMed_21979375_A2Up0.3606997420
GSE35957Up0.1404609493
GSE36640Up0.1116166672
GSE54402Down-0.0839567284
GSE9593Up0.0204022633
GSE43922Up0.1617341723
GSE24585Up0.0377467483
GSE37065Down-0.0558121195
GSE28863_A1Down-0.0107956964
GSE28863_A2Up0.0628580219
GSE28863_A3Up0.1093783695
GSE28863_A4Down-0.0267615147
GSE48662Down-0.0415077552

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.