HCSGD entry for EDN3

1. General information

Official gene symbolEDN3
Entrez ID1908
Gene full nameendothelin 3
Other gene symbolsET-3 ET3 HSCR4 PPET3 WS4B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001755Neural crest cell migrationIEAbiological_process
GO:0002690Positive regulation of leukocyte chemotaxisIDAbiological_process
GO:0003100Regulation of systemic arterial blood pressure by endothelinIDAbiological_process
GO:0005102Receptor bindingTASmolecular_function
GO:0005179Hormone activityIDAmolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007166Cell surface receptor signaling pathwayIDAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008015Blood circulationTASbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0010460Positive regulation of heart rateIDAbiological_process
GO:0014824Artery smooth muscle contractionIDAbiological_process
GO:0014826Vein smooth muscle contractionIDAbiological_process
GO:0019229Regulation of vasoconstrictionIEAbiological_process
GO:0030072Peptide hormone secretionIDAbiological_process
GO:0030182Neuron differentiationIEAbiological_process
GO:0030318Melanocyte differentiationIEAbiological_process
GO:0030593Neutrophil chemotaxisIDAbiological_process
GO:0042310VasoconstrictionIDAbiological_process
GO:0043406Positive regulation of MAP kinase activityIDAbiological_process
GO:0045840Positive regulation of mitosisIDAbiological_process
GO:0046887Positive regulation of hormone secretionIDAbiological_process
GO:0048016Inositol phosphate-mediated signalingIDAbiological_process
GO:0048070Regulation of developmental pigmentationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73720298620.86687343570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0294123105
GSE13712_SHEARUp0.1698711663
GSE13712_STATICUp0.0448871534
GSE19018Down-0.0313320413
GSE19899_A1Down-0.0346871038
GSE19899_A2Up0.0819973080
PubMed_21979375_A1Up0.0916622582
PubMed_21979375_A2Down-0.1054916765
GSE35957Up0.0068457104
GSE36640Down-0.0761867554
GSE54402Up0.0399987917
GSE9593Up0.1014550692
GSE43922Up0.0587538906
GSE24585Down-0.0500480474
GSE37065Up0.0172333236
GSE28863_A1Down-0.0363440400
GSE28863_A2Down-0.0903215684
GSE28863_A3Up0.3443853588
GSE28863_A4Up0.0648025472
GSE48662Down-0.0206231016

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.