HCSGD entry for ACAD8

1. General information

Official gene symbolACAD8
Entrez ID27034
Gene full nameacyl-CoA dehydrogenase family, member 8
Other gene symbolsACAD-8 ARC42
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003995Acyl-CoA dehydrogenase activityEXP IEAmolecular_function
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006574Valine catabolic processIEAbiological_process
GO:0006629Lipid metabolic processTASbiological_process
GO:0009083Branched-chain amino acid catabolic processTASbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02644627480.79158631510.37947192601.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5506041778
GSE13712_SHEARDown-0.1571391470
GSE13712_STATICDown-0.3514286039
GSE19018Down-0.7262261944
GSE19899_A1Up1.0768146681
GSE19899_A2Up0.5613652388
PubMed_21979375_A1Up0.0056751907
PubMed_21979375_A2Up0.9711175638
GSE35957Down-0.1711259699
GSE36640Up0.9622002778
GSE54402Up0.5041523224
GSE9593Down-0.2882352072
GSE43922Up0.4698173718
GSE24585Up0.4662801518
GSE37065Up0.0276801891
GSE28863_A1Down-0.0218700470
GSE28863_A2Up0.1255251147
GSE28863_A3Down-0.2523694105
GSE28863_A4Up0.0772301640
GSE48662Down-0.1156383806

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Methacrylyl-Coenzyme ADB01675 EXPT00129

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7a-5pMIMAT0000062MIRT052639CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.