HCSGD entry for ACAD8

1. General information

Official gene symbolACAD8
Entrez ID27034
Gene full nameacyl-CoA dehydrogenase family, member 8
Other gene symbolsACAD-8 ARC42
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003995Acyl-CoA dehydrogenase activityEXP IEAmolecular_function
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006574Valine catabolic processIEAbiological_process
GO:0006629Lipid metabolic processTASbiological_process
GO:0009083Branched-chain amino acid catabolic processTASbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02644627480.79158631510.37947192601.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5506041778
GSE13712_SHEARDown-0.1571391470
GSE13712_STATICDown-0.3514286039
GSE19018Down-0.7262261944
GSE19899_A1Up1.0768146681
GSE19899_A2Up0.5613652388
PubMed_21979375_A1Up0.0056751907
PubMed_21979375_A2Up0.9711175638
GSE35957Down-0.1711259699
GSE36640Up0.9622002778
GSE54402Up0.5041523224
GSE9593Down-0.2882352072
GSE43922Up0.4698173718
GSE24585Up0.4662801518
GSE37065Up0.0276801891
GSE28863_A1Down-0.0218700470
GSE28863_A2Up0.1255251147
GSE28863_A3Down-0.2523694105
GSE28863_A4Up0.0772301640
GSE48662Down-0.1156383806

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Methacrylyl-Coenzyme ADB01675 EXPT00129

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7a-5pMIMAT0000062MIRT052639CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.