HCSGD entry for HOXD10

1. General information

Official gene symbolHOXD10
Entrez ID3236
Gene full namehomeobox D10
Other gene symbolsHOX4 HOX4D HOX4E Hox-4.4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007519Skeletal muscle tissue developmentIEAbiological_process
GO:0008344Adult locomotory behaviorIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0009954Proximal/distal pattern formationIEAbiological_process
GO:0021520Spinal cord motor neuron cell fate specificationIEAbiological_process
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0035136Forelimb morphogenesisIEAbiological_process
GO:0035137Hindlimb morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0048935Peripheral nervous system neuron developmentIEAbiological_process
GO:0050905Neuromuscular processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18037076480.85668160780.83235826331.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0131804382
GSE13712_SHEARDown-0.0193529736
GSE13712_STATICDown-0.0083737623
GSE19018Up0.0939199133
GSE19899_A1Up0.2060720948
GSE19899_A2Up0.0736019891
PubMed_21979375_A1Down-0.4686473683
PubMed_21979375_A2Up0.0593840330
GSE35957Up0.0884350549
GSE36640Up0.0925098938
GSE54402Down-0.0134229692
GSE9593Down-0.0169869251
GSE43922Up0.2576917347
GSE24585Up1.3163918686
GSE37065Up0.2695240297
GSE28863_A1Up0.0586992405
GSE28863_A2Up0.0072947652
GSE28863_A3Up0.1782866439
GSE28863_A4Down-0.1883601842
GSE48662Up0.1912195548

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-10b-5pMIMAT0000254MIRT002021Luciferase reporter assay//Reporter assayFunctional MTI17898713
hsa-miR-10b-5pMIMAT0000254MIRT002021Luciferase reporter assay//Western blotFunctional MTI21419107
hsa-miR-10b-5pMIMAT0000254MIRT002021Luciferase reporter assayFunctional MTI23034333
hsa-miR-10b-5pMIMAT0000254MIRT002021Reporter assayFunctional MTI21642433
hsa-miR-339-5pMIMAT0000764MIRT042798CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-10b-5pMIMAT00002541hsa-miR-10b{Western blot}{overexpression}17898713
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.