HCSGD entry for HOXD10
1. General information
| Official gene symbol | HOXD10 |
|---|---|
| Entrez ID | 3236 |
| Gene full name | homeobox D10 |
| Other gene symbols | HOX4 HOX4D HOX4E Hox-4.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007519 | Skeletal muscle tissue development | IEA | biological_process |
| GO:0008344 | Adult locomotory behavior | IEA | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0009954 | Proximal/distal pattern formation | IEA | biological_process |
| GO:0021520 | Spinal cord motor neuron cell fate specification | IEA | biological_process |
| GO:0030326 | Embryonic limb morphogenesis | IEA | biological_process |
| GO:0035136 | Forelimb morphogenesis | IEA | biological_process |
| GO:0035137 | Hindlimb morphogenesis | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
| GO:0048935 | Peripheral nervous system neuron development | IEA | biological_process |
| GO:0050905 | Neuromuscular process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1803707648 | 0.8566816078 | 0.8323582633 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0131804382 |
| GSE13712_SHEAR | Down | -0.0193529736 |
| GSE13712_STATIC | Down | -0.0083737623 |
| GSE19018 | Up | 0.0939199133 |
| GSE19899_A1 | Up | 0.2060720948 |
| GSE19899_A2 | Up | 0.0736019891 |
| PubMed_21979375_A1 | Down | -0.4686473683 |
| PubMed_21979375_A2 | Up | 0.0593840330 |
| GSE35957 | Up | 0.0884350549 |
| GSE36640 | Up | 0.0925098938 |
| GSE54402 | Down | -0.0134229692 |
| GSE9593 | Down | -0.0169869251 |
| GSE43922 | Up | 0.2576917347 |
| GSE24585 | Up | 1.3163918686 |
| GSE37065 | Up | 0.2695240297 |
| GSE28863_A1 | Up | 0.0586992405 |
| GSE28863_A2 | Up | 0.0072947652 |
| GSE28863_A3 | Up | 0.1782866439 |
| GSE28863_A4 | Down | -0.1883601842 |
| GSE48662 | Up | 0.1912195548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10b-5p | MIMAT0000254 | MIRT002021 | Luciferase reporter assay//Reporter assay | Functional MTI | 17898713 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT002021 | Luciferase reporter assay//Western blot | Functional MTI | 21419107 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT002021 | Luciferase reporter assay | Functional MTI | 23034333 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT002021 | Reporter assay | Functional MTI | 21642433 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042798 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-10b-5p | MIMAT0000254 | 1 | hsa-miR-10b | {Western blot} | {overexpression} | 17898713 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
