HCSGD entry for ARNT

1. General information

Official gene symbolARNT
Entrez ID405
Gene full namearyl hydrocarbon receptor nuclear translocator
Other gene symbolsHIF-1-beta HIF-1beta HIF1-beta HIF1B HIF1BETA TANGO bHLHe2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIDAbiological_process
GO:0001892Embryonic placenta developmentIEAbiological_process
GO:0001938Positive regulation of endothelial cell proliferationICbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEA TASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003713Transcription coactivator activityIEAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0004874Aryl hydrocarbon receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEA TASbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0010575Positive regulation vascular endothelial growth factor productionIDAbiological_process
GO:0017162Aryl hydrocarbon receptor bindingIPImolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030949Positive regulation of vascular endothelial growth factor receptor signaling pathwayICbiological_process
GO:0033235Positive regulation of protein sumoylationIEAbiological_process
GO:0042789MRNA transcription from RNA polymerase II promoterICbiological_process
GO:0043565Sequence-specific DNA bindingIDAmolecular_function
GO:0043619Regulation of transcription from RNA polymerase II promoter in response to oxidative stressIDAbiological_process
GO:0045648Positive regulation of erythrocyte differentiationICbiological_process
GO:0045821Positive regulation of glycolysisICbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046886Positive regulation of hormone biosynthetic processIDAbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0061418Regulation of transcription from RNA polymerase II promoter in response to hypoxiaTASbiological_process
GO:0071456Cellular response to hypoxiaTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19211972190.69213903730.85064464051.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2070855118
GSE13712_SHEARDown-0.1449044588
GSE13712_STATICDown-0.0713691011
GSE19018Up0.0828454607
GSE19899_A1Up0.0832237483
GSE19899_A2Up0.2338106339
PubMed_21979375_A1Up0.1396791450
PubMed_21979375_A2Up0.1662396529
GSE35957Up0.2279803648
GSE36640Up0.1590074102
GSE54402Down-0.2105940309
GSE9593Up0.0815995422
GSE43922Up0.1525275782
GSE24585Up0.4090618289
GSE37065Down-0.0104054359
GSE28863_A1Up0.5917753573
GSE28863_A2Up0.6627403826
GSE28863_A3Down-0.2444000448
GSE28863_A4Down-0.4480697437
GSE48662Down-0.0434450146

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-107MIMAT0000104MIRT004537qRT-PCR//Luciferase reporter assay//Western blot//Northern blot//Reporter assay;Western blotFunctional MTI20308559
hsa-miR-877-3pMIMAT0004950MIRT037117CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043236CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.