HCSGD entry for ATP2B2

1. General information

Official gene symbolATP2B2
Entrez ID491
Gene full nameATPase, Ca++ transporting, plasma membrane 2
Other gene symbolsPMCA2 PMCA2a PMCA2i
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005388Calcium-transporting ATPase activityIDA IEA NASmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIDA IEAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA NAS TAScellular_component
GO:0005929CiliumIEAcellular_component
GO:0006200ATP catabolic processIDA NASbiological_process
GO:0006810TransportIDA NASbiological_process
GO:0006812Cation transportIDAbiological_process
GO:0006816Calcium ion transportIMPbiological_process
GO:0006996Organelle organizationIEAbiological_process
GO:0007595LactationIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0007605Sensory perception of soundIMPbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008152Metabolic processIDAbiological_process
GO:0008361Regulation of cell sizeIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0021702Cerebellar Purkinje cell differentiationIEAbiological_process
GO:0021707Cerebellar granule cell differentiationIEAbiological_process
GO:0030001Metal ion transportIDAbiological_process
GO:0030165PDZ domain bindingIDAmolecular_function
GO:0030182Neuron differentiationIDAbiological_process
GO:0030899Calcium-dependent ATPase activityIEAmolecular_function
GO:0034220Ion transmembrane transportIDA TASbiological_process
GO:0040011LocomotionIEAbiological_process
GO:0042428Serotonin metabolic processIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045299Otolith mineralizationIEAbiological_process
GO:0046068CGMP metabolic processIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048167Regulation of synaptic plasticityIEAbiological_process
GO:0050808Synapse organizationIEAbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0050910Detection of mechanical stimulus involved in sensory perception of soundIEAbiological_process
GO:0051480Cytosolic calcium ion homeostasisIMPbiological_process
GO:0051928Positive regulation of calcium ion transportIEAbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0060088Auditory receptor cell stereocilium organizationIEAbiological_process
GO:0070588Calcium ion transmembrane transportIDAbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
GO:0090102Cochlea developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54363015840.89288189660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0473773494
GSE13712_SHEARDown-0.0799958784
GSE13712_STATICDown-0.0705919319
GSE19018Up0.0735615988
GSE19899_A1Up0.0171371644
GSE19899_A2Up0.0374019446
PubMed_21979375_A1Up0.0238756486
PubMed_21979375_A2Up0.0000136213
GSE35957Up0.0179857655
GSE36640Up0.0415285931
GSE54402Down-0.0252359214
GSE9593Up0.0039077403
GSE43922Up0.0219377356
GSE24585Up0.0397892778
GSE37065Down-0.0207942173
GSE28863_A1Down-0.1486311497
GSE28863_A2Up0.2612144388
GSE28863_A3Up0.2945653550
GSE28863_A4Up0.2893069276
GSE48662Up0.2037946511

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.