HCSGD entry for ATP2B2

1. General information

Official gene symbolATP2B2
Entrez ID491
Gene full nameATPase, Ca++ transporting, plasma membrane 2
Other gene symbolsPMCA2 PMCA2a PMCA2i
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005388Calcium-transporting ATPase activityIDA IEA NASmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIDA IEAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA NAS TAScellular_component
GO:0005929CiliumIEAcellular_component
GO:0006200ATP catabolic processIDA NASbiological_process
GO:0006810TransportIDA NASbiological_process
GO:0006812Cation transportIDAbiological_process
GO:0006816Calcium ion transportIMPbiological_process
GO:0006996Organelle organizationIEAbiological_process
GO:0007595LactationIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0007605Sensory perception of soundIMPbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008152Metabolic processIDAbiological_process
GO:0008361Regulation of cell sizeIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0021702Cerebellar Purkinje cell differentiationIEAbiological_process
GO:0021707Cerebellar granule cell differentiationIEAbiological_process
GO:0030001Metal ion transportIDAbiological_process
GO:0030165PDZ domain bindingIDAmolecular_function
GO:0030182Neuron differentiationIDAbiological_process
GO:0030899Calcium-dependent ATPase activityIEAmolecular_function
GO:0034220Ion transmembrane transportIDA TASbiological_process
GO:0040011LocomotionIEAbiological_process
GO:0042428Serotonin metabolic processIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045299Otolith mineralizationIEAbiological_process
GO:0046068CGMP metabolic processIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048167Regulation of synaptic plasticityIEAbiological_process
GO:0050808Synapse organizationIEAbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0050910Detection of mechanical stimulus involved in sensory perception of soundIEAbiological_process
GO:0051480Cytosolic calcium ion homeostasisIMPbiological_process
GO:0051928Positive regulation of calcium ion transportIEAbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0060088Auditory receptor cell stereocilium organizationIEAbiological_process
GO:0070588Calcium ion transmembrane transportIDAbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
GO:0090102Cochlea developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54363015840.89288189660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0473773494
GSE13712_SHEARDown-0.0799958784
GSE13712_STATICDown-0.0705919319
GSE19018Up0.0735615988
GSE19899_A1Up0.0171371644
GSE19899_A2Up0.0374019446
PubMed_21979375_A1Up0.0238756486
PubMed_21979375_A2Up0.0000136213
GSE35957Up0.0179857655
GSE36640Up0.0415285931
GSE54402Down-0.0252359214
GSE9593Up0.0039077403
GSE43922Up0.0219377356
GSE24585Up0.0397892778
GSE37065Down-0.0207942173
GSE28863_A1Down-0.1486311497
GSE28863_A2Up0.2612144388
GSE28863_A3Up0.2945653550
GSE28863_A4Up0.2893069276
GSE48662Up0.2037946511

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.