HCSGD entry for PRKAG2

1. General information

Official gene symbolPRKAG2
Entrez ID51422
Gene full nameprotein kinase, AMP-activated, gamma 2 non-catalytic subunit
Other gene symbolsAAKG AAKG2 CMH6 H91620p WPWS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004862CAMP-dependent protein kinase inhibitor activityIDAmolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005977Glycogen metabolic processIMPbiological_process
GO:0006110Regulation of glycolysisIMPbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0006633Fatty acid biosynthetic processIEAbiological_process
GO:0006754ATP biosynthetic processTASbiological_process
GO:0006853Carnitine shuttleTASbiological_process
GO:0007050Cell cycle arrestTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008603CAMP-dependent protein kinase regulator activityIMPmolecular_function
GO:0008607Phosphorylase kinase regulator activityIMPmolecular_function
GO:0010800Positive regulation of peptidyl-threonine phosphorylationIMPbiological_process
GO:0016126Sterol biosynthetic processTASbiological_process
GO:0016208AMP bindingIEAmolecular_function
GO:0019217Regulation of fatty acid metabolic processIMPbiological_process
GO:0019901Protein kinase bindingIDA IEAmolecular_function
GO:0030295Protein kinase activator activityIMPmolecular_function
GO:0030554Adenyl nucleotide bindingIEAmolecular_function
GO:0031588AMP-activated protein kinase complexIDA IEAcellular_component
GO:0035556Intracellular signal transductionIMPbiological_process
GO:0042304Regulation of fatty acid biosynthetic processTASbiological_process
GO:0043531ADP bindingIDAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045860Positive regulation of protein kinase activityIMPbiological_process
GO:0046320Regulation of fatty acid oxidationTASbiological_process
GO:0046324Regulation of glucose importTASbiological_process
GO:0050790Regulation of catalytic activityIEAbiological_process
GO:0071901Negative regulation of protein serine/threonine kinase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91009947190.06873657160.99999024730.4947377905

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2723802034
GSE13712_SHEARUp0.2962109967
GSE13712_STATICUp0.3961116567
GSE19018Up0.0373994829
GSE19899_A1Down-0.5188198592
GSE19899_A2Down-0.0939385637
PubMed_21979375_A1Down-0.0100524755
PubMed_21979375_A2Down-0.4926114153
GSE35957Down-0.3782496479
GSE36640Down-0.2154246575
GSE54402Down-0.7830072131
GSE9593Up0.0416648006
GSE43922Down-0.3234031752
GSE24585Down-0.1158575311
GSE37065Down-0.0578363029
GSE28863_A1Up0.0757331644
GSE28863_A2Up0.1012341364
GSE28863_A3Up0.1350516253
GSE28863_A4Up0.0178013349
GSE48662Down-0.0531447064

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.