HCSGD entry for PRKAG2

1. General information

Official gene symbolPRKAG2
Entrez ID51422
Gene full nameprotein kinase, AMP-activated, gamma 2 non-catalytic subunit
Other gene symbolsAAKG AAKG2 CMH6 H91620p WPWS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004862CAMP-dependent protein kinase inhibitor activityIDAmolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005977Glycogen metabolic processIMPbiological_process
GO:0006110Regulation of glycolysisIMPbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0006633Fatty acid biosynthetic processIEAbiological_process
GO:0006754ATP biosynthetic processTASbiological_process
GO:0006853Carnitine shuttleTASbiological_process
GO:0007050Cell cycle arrestTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008603CAMP-dependent protein kinase regulator activityIMPmolecular_function
GO:0008607Phosphorylase kinase regulator activityIMPmolecular_function
GO:0010800Positive regulation of peptidyl-threonine phosphorylationIMPbiological_process
GO:0016126Sterol biosynthetic processTASbiological_process
GO:0016208AMP bindingIEAmolecular_function
GO:0019217Regulation of fatty acid metabolic processIMPbiological_process
GO:0019901Protein kinase bindingIDA IEAmolecular_function
GO:0030295Protein kinase activator activityIMPmolecular_function
GO:0030554Adenyl nucleotide bindingIEAmolecular_function
GO:0031588AMP-activated protein kinase complexIDA IEAcellular_component
GO:0035556Intracellular signal transductionIMPbiological_process
GO:0042304Regulation of fatty acid biosynthetic processTASbiological_process
GO:0043531ADP bindingIDAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045860Positive regulation of protein kinase activityIMPbiological_process
GO:0046320Regulation of fatty acid oxidationTASbiological_process
GO:0046324Regulation of glucose importTASbiological_process
GO:0050790Regulation of catalytic activityIEAbiological_process
GO:0071901Negative regulation of protein serine/threonine kinase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91009947190.06873657160.99999024730.4947377905

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2723802034
GSE13712_SHEARUp0.2962109967
GSE13712_STATICUp0.3961116567
GSE19018Up0.0373994829
GSE19899_A1Down-0.5188198592
GSE19899_A2Down-0.0939385637
PubMed_21979375_A1Down-0.0100524755
PubMed_21979375_A2Down-0.4926114153
GSE35957Down-0.3782496479
GSE36640Down-0.2154246575
GSE54402Down-0.7830072131
GSE9593Up0.0416648006
GSE43922Down-0.3234031752
GSE24585Down-0.1158575311
GSE37065Down-0.0578363029
GSE28863_A1Up0.0757331644
GSE28863_A2Up0.1012341364
GSE28863_A3Up0.1350516253
GSE28863_A4Up0.0178013349
GSE48662Down-0.0531447064

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.