HCSGD entry for PEX1
1. General information
| Official gene symbol | PEX1 |
|---|---|
| Entrez ID | 5189 |
| Gene full name | peroxisomal biogenesis factor 1 |
| Other gene symbols | PBD1A PBD1B ZWS ZWS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA IMP | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IMP | biological_process |
| GO:0006625 | Protein targeting to peroxisome | IEA IMP | biological_process |
| GO:0007031 | Peroxisome organization | IMP | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0008152 | Metabolic process | IMP | biological_process |
| GO:0016558 | Protein import into peroxisome matrix | IMP | biological_process |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0042623 | ATPase activity, coupled | IEA IMP | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0060152 | Microtubule-based peroxisome localization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9631328141 | 0.0207642073 | 0.9999902473 | 0.2784180846 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1020418701 |
| GSE13712_SHEAR | Down | -0.5447613034 |
| GSE13712_STATIC | Down | -0.0532156219 |
| GSE19018 | Up | 0.0937292123 |
| GSE19899_A1 | Down | -0.3580615500 |
| GSE19899_A2 | Down | -0.8141250395 |
| PubMed_21979375_A1 | Down | -1.0120209251 |
| PubMed_21979375_A2 | Down | -0.4775605861 |
| GSE35957 | Down | -0.1365542785 |
| GSE36640 | Up | 0.0302796380 |
| GSE54402 | Down | -0.4200545274 |
| GSE9593 | Down | -0.2060470817 |
| GSE43922 | Down | -0.5564721857 |
| GSE24585 | Up | 0.3097764331 |
| GSE37065 | Up | 0.0958031744 |
| GSE28863_A1 | Up | 0.0369199595 |
| GSE28863_A2 | Up | 0.4944081263 |
| GSE28863_A3 | Down | -0.6264298810 |
| GSE28863_A4 | Down | -0.2350549576 |
| GSE48662 | Down | -0.5718217696 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT046918 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
