HCSGD entry for PEX1

1. General information

Official gene symbolPEX1
Entrez ID5189
Gene full nameperoxisomal biogenesis factor 1
Other gene symbolsPBD1A PBD1B ZWS ZWS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEA IMPmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005778Peroxisomal membraneIDA IEAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006200ATP catabolic processIMPbiological_process
GO:0006625Protein targeting to peroxisomeIEA IMPbiological_process
GO:0007031Peroxisome organizationIMPbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008152Metabolic processIMPbiological_process
GO:0016558Protein import into peroxisome matrixIMPbiological_process
GO:0032403Protein complex bindingIDAmolecular_function
GO:0042623ATPase activity, coupledIEA IMPmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0060152Microtubule-based peroxisome localizationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96313281410.02076420730.99999024730.2784180846

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1020418701
GSE13712_SHEARDown-0.5447613034
GSE13712_STATICDown-0.0532156219
GSE19018Up0.0937292123
GSE19899_A1Down-0.3580615500
GSE19899_A2Down-0.8141250395
PubMed_21979375_A1Down-1.0120209251
PubMed_21979375_A2Down-0.4775605861
GSE35957Down-0.1365542785
GSE36640Up0.0302796380
GSE54402Down-0.4200545274
GSE9593Down-0.2060470817
GSE43922Down-0.5564721857
GSE24585Up0.3097764331
GSE37065Up0.0958031744
GSE28863_A1Up0.0369199595
GSE28863_A2Up0.4944081263
GSE28863_A3Down-0.6264298810
GSE28863_A4Down-0.2350549576
GSE48662Down-0.5718217696

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-221-3pMIMAT0000278MIRT046918CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.