HCSGD entry for SARS2


1. General information

Official gene symbolSARS2
Entrez ID54938
Gene full nameseryl-tRNA synthetase 2, mitochondrial
Other gene symbolsSARS SARSM SERS SYS SerRS SerRSmt mtSerRS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004828Serine-tRNA ligase activityIEA ISS TASmolecular_function
GO:0005524ATP bindingIEA ISSmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005739MitochondrionISScellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006434Seryl-tRNA aminoacylationIEA ISSbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0030163Protein catabolic processIEAbiological_process
GO:0097056Selenocysteinyl-tRNA(Sec) biosynthetic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93504398770.14955038940.99999024730.7474536358

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1067321175
GSE13712_SHEARDown-0.1011352660
GSE13712_STATICDown-0.1346955269
GSE19018Down-0.3197703332
GSE19899_A1Down-0.1881262665
GSE19899_A2Down-0.1050049064
PubMed_21979375_A1Up1.2258504402
PubMed_21979375_A2Up0.2450891707
GSE35957Down-0.2562153696
GSE36640Down-0.3593282727
GSE54402Up0.3028109201
GSE9593Down-0.5829102358
GSE43922Down-0.0092027702
GSE24585Down-0.1851317573
GSE37065Down-0.0896914310
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1854680047

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT041208CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043094CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049346CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.