HCSGD entry for SARS2
1. General information
| Official gene symbol | SARS2 |
|---|---|
| Entrez ID | 54938 |
| Gene full name | seryl-tRNA synthetase 2, mitochondrial |
| Other gene symbols | SARS SARSM SERS SYS SerRS SerRSmt mtSerRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004828 | Serine-tRNA ligase activity | IEA ISS TAS | molecular_function |
| GO:0005524 | ATP binding | IEA ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006434 | Seryl-tRNA aminoacylation | IEA ISS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030163 | Protein catabolic process | IEA | biological_process |
| GO:0097056 | Selenocysteinyl-tRNA(Sec) biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9350439877 | 0.1495503894 | 0.9999902473 | 0.7474536358 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1067321175 |
| GSE13712_SHEAR | Down | -0.1011352660 |
| GSE13712_STATIC | Down | -0.1346955269 |
| GSE19018 | Down | -0.3197703332 |
| GSE19899_A1 | Down | -0.1881262665 |
| GSE19899_A2 | Down | -0.1050049064 |
| PubMed_21979375_A1 | Up | 1.2258504402 |
| PubMed_21979375_A2 | Up | 0.2450891707 |
| GSE35957 | Down | -0.2562153696 |
| GSE36640 | Down | -0.3593282727 |
| GSE54402 | Up | 0.3028109201 |
| GSE9593 | Down | -0.5829102358 |
| GSE43922 | Down | -0.0092027702 |
| GSE24585 | Down | -0.1851317573 |
| GSE37065 | Down | -0.0896914310 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1854680047 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041208 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043094 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049346 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
