HCSGD entry for RIC8B
1. General information
| Official gene symbol | RIC8B |
|---|---|
| Entrez ID | 55188 |
| Gene full name | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) |
| Other gene symbols | RIC8 hSyn |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001965 | G-protein alpha-subunit binding | IDA | molecular_function |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8257890050 | 0.4698883667 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0770087880 |
| GSE13712_SHEAR | Down | -0.1763289643 |
| GSE13712_STATIC | Up | 0.0267050615 |
| GSE19018 | Down | -0.1105466693 |
| GSE19899_A1 | Down | -0.0897580153 |
| GSE19899_A2 | Down | -0.1359270100 |
| PubMed_21979375_A1 | Down | -0.4192732687 |
| PubMed_21979375_A2 | Up | 0.0669180048 |
| GSE35957 | Down | -0.1488656359 |
| GSE36640 | Down | -0.0376082868 |
| GSE54402 | Up | 0.0648858613 |
| GSE9593 | Up | 0.0625328151 |
| GSE43922 | Up | 0.0523173292 |
| GSE24585 | Down | -0.1017946218 |
| GSE37065 | Up | 0.1556662262 |
| GSE28863_A1 | Up | 0.1172259529 |
| GSE28863_A2 | Up | 0.1168334015 |
| GSE28863_A3 | Down | -0.5129129231 |
| GSE28863_A4 | Up | 0.1689993286 |
| GSE48662 | Down | -0.1727055580 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024719 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026881 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
