HCSGD entry for RIC8B


1. General information

Official gene symbolRIC8B
Entrez ID55188
Gene full nameresistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
Other gene symbolsRIC8 hSyn
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001965G-protein alpha-subunit bindingIDAmolecular_function
GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82578900500.46988836670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0770087880
GSE13712_SHEARDown-0.1763289643
GSE13712_STATICUp0.0267050615
GSE19018Down-0.1105466693
GSE19899_A1Down-0.0897580153
GSE19899_A2Down-0.1359270100
PubMed_21979375_A1Down-0.4192732687
PubMed_21979375_A2Up0.0669180048
GSE35957Down-0.1488656359
GSE36640Down-0.0376082868
GSE54402Up0.0648858613
GSE9593Up0.0625328151
GSE43922Up0.0523173292
GSE24585Down-0.1017946218
GSE37065Up0.1556662262
GSE28863_A1Up0.1172259529
GSE28863_A2Up0.1168334015
GSE28863_A3Down-0.5129129231
GSE28863_A4Up0.1689993286
GSE48662Down-0.1727055580

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024719MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026881MicroarrayFunctional MTI (Weak)19074876
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.